Clinical & Therapeutic Research

Clinical Outcome References
for Threat Modeling.

76 of 161 catalogued BCI attack techniques reference symptoms matching DSM-5-TR diagnostic criteria. Separately, 130 of 161 share their core mechanism with FDA-recognized therapeutic applications. These are distinct data sets: a technique may have a psychiatric outcome mapping, a therapeutic analog, both, or neither. All mappings require clinical validation.

DSM-5 mapped
of 161 techniques

130

therapeutic
analogs mapped

DSM-5-TR
diagnoses linked

336

treatable
conditions

Threat Modeling Reference Only — Not Diagnostic Guidance

These DSM-5-TR references and therapeutic dual-use mappings are used strictly for security threat modeling — illustrating the potential clinical severity of sustained BCI attack patterns. They are not diagnostic claims and have not been reviewed or validated by psychiatrists or clinical neuroscientists.

Neuromodest caveat (Morse, 2006): Neuroscience does not yet fully understand how the brain produces cognition, emotion, or consciousness. Neural correlates do not prove causation. The mappings here reflect current knowledge of neuroanatomical pathways and functional neuroscience, but this knowledge is incomplete and actively evolving.

Clinical validation, interrater reliability studies, and expert panel review are required before these references can inform clinical decision-making. See Section 9 of the working paper.

For Clinicians

A patient presents with sudden-onset anxiety, depersonalization, or motor tics — and they have a brain-computer interface. Is this a psychiatric condition, a device malfunction, or an attack? Today, there is no clinical framework to help you differentiate.

This page maps 76 attack techniques to DSM-5-TR diagnostic categories and 130 techniques to their therapeutic analogs — the same mechanisms used in FDA-recognized treatments. The confidence level indicates whether the pathway is established in neuroscience literature, probable based on mechanism, or theoretical.

This is not diagnostic guidance. It is a threat modeling reference that helps clinicians understand what is technically possible when a neural device is compromised — so that emerging symptom presentations can be evaluated in context.

Neural Impact Chain — Interactive

Psychiatric Outcome Mappings

76 of 161 techniques reference DSM-5-TR diagnostic categories for threat modeling purposes.

Diagnostic Clusters

Attack techniques are grouped into four diagnostic clusters based on their primary psychiatric outcome pattern. Each cluster represents a family of related symptoms that emerge from similar neural disruption mechanisms.

Non-Diagnostic

Mood/Trauma

Motor/Neurocognitive

Cognitive/Psychotic

Persistent/Personality

Mood / Trauma 27 techniques

Attacks that disrupt limbic circuitry — primarily amygdala, hippocampus, and prefrontal connectivity. Present as depression, anxiety, PTSD-like symptoms, adjustment disorders. Most common cluster because emotional regulation pathways are the most accessible via neurostimulation.

Cognitive / Psychotic 22 techniques

Attacks targeting cortical processing, thalamocortical loops, and dopaminergic pathways. Can produce perceptual distortions, hallucinations, thought disorganization, and cognitive impairment that mimics schizophrenia spectrum, ADHD, or neurocognitive disorders.

Motor / Neurocognitive 26 techniques

Attacks disrupting motor cortex, basal ganglia, cerebellum, or spinal cord pathways. Manifest as involuntary movements, coordination deficits, conversion-like symptoms, or progressive neurocognitive decline. Often the most clinically visible outcomes.

Persistent / Personality 9 techniques

Attacks causing sustained alterations to personality, identity, or behavioral regulation through prolonged or repeated neural manipulation. The most concerning cluster for neurorights — these changes can persist after the attack ceases.

Risk Classification

Direct Risk

The attack mechanism directly causes the psychiatric outcome through a documented neural pathway.

Indirect Risk

The psychiatric outcome arises secondary to the primary neurological disruption.

Evidence Confidence

Each technique-to-diagnosis link is classified by the strength of the underlying neuroscience evidence connecting the attack mechanism to the clinical outcome.

established (398)

probable (22)

Established (398) — published neuroscience evidence Probable (22) — strong mechanistic basis

Diagnosis Explorer

46 DSM-5-TR diagnoses linked to 76 attack techniques. Expand any diagnosis to see the techniques that can produce it, with their neural pathways and NISS severity scores.

F20 Schizophrenia Spectrum 48 techniques (47 primary, 1 secondary)

QIF-T0002

Neural ransomware

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Cognitive/Psychotic NISS 6.1 direct

QIF-T0008

Command hijacking

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Cognitive/Psychotic NISS 6.1 direct

QIF-T0009

RF false brainwave injection

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Cognitive/Psychotic NISS 7.4 direct

QIF-T0010

ELF neural entrainment

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Cognitive/Psychotic NISS 7.4 direct

QIF-T0011

Intermodulation (BCI signal weaponized)

Pathway: N6 (hippocampus/amygdala) → emotion regulation; N5 (striatum/STN) → motor selection

Mood/Trauma NISS 7.4 direct

QIF-T0012

Pulsed microwave (Frey effect)

Pathway: N7 (PFC/M1) → executive function; N2 (medulla/pons) → vital functions

Mood/Trauma NISS 5.4 indirect

QIF-T0013

Temporal interference (deep targeting)

Pathway: N6 (hippocampus/amygdala) → emotion regulation; N5 (striatum/STN) → motor selection

Mood/Trauma NISS 7.4 direct

QIF-T0014

Envelope modulation (stealth carrier)

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 8.1 direct

QIF-T0022

Neurofeedback falsification

Pathway: N7 (PFC/M1) → executive function

Persistent/Personality NISS 8.1 direct

QIF-T0023

Closed-loop perturbation cascade

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 7.4 direct

QIF-T0025

Neuronal jamming

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 5.4 direct

QIF-T0026

Neuronal flooding

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 6.1 direct

QIF-T0027

Neuronal scanning

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 3.4 direct

QIF-T0029

Neural DoS (stimulation flood)

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 6.1 direct

QIF-T0030

Motor hijacking

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 6.7 direct

QIF-T0032

Identity spoofing (neural biometric)

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 2.7 direct

QIF-T0033

Identity erosion (long-term personality drift)

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Persistent/Personality NISS 8 direct

QIF-T0034

Working memory poisoning

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 5.4 direct

QIF-T0035

P300 interrogation

Pathway: N7 (PFC/M1) → executive function

Cognitive/Psychotic NISS 2.7 direct

QIF-T0036

Thought decoding (covert speech)

Pathway: N7 (PFC/M1) → executive function

Cognitive/Psychotic NISS 3.4 direct

QIF-T0037

Agency manipulation

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Cognitive/Psychotic NISS 7.4 direct

QIF-T0038

Brainprint theft

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 4.7 direct

QIF-T0039

Self-model corruption

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Persistent/Personality NISS 8 direct

QIF-T0040

Neurophishing

Pathway: N7 (PFC/M1) → executive function

Cognitive/Psychotic NISS 5.4 indirect

QIF-T0041

Cognitive biometric inference

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 2.7 direct

QIF-T0052

ERP harvesting

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 2.7 direct

QIF-T0053

Cognitive state capture

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 2.7 direct

QIF-T0054

Memory extraction

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 3.4 direct

QIF-T0055

BCI cognitive warfare

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Cognitive/Psychotic NISS 8.1 indirect

QIF-T0056

Neuro-surveillance

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 2.7 direct

QIF-T0059

Pattern lock (learned pathway persistence)

Pathway: N7 (PFC/M1) → executive function

Persistent/Personality NISS 7.4 direct

QIF-T0060

Memory implant (cross-session persistence)

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Persistent/Personality NISS 7.4 direct

QIF-T0062

Gradual drift (slow parameter shift)

Pathway: N7 (PFC/M1) → executive function

Persistent/Personality NISS 7.4 direct

QIF-T0064

User consent fatigue (neural permission flooding)

Pathway: N7 (PFC/M1) → executive function

Cognitive/Psychotic NISS 4.7 indirect

QIF-T0065

Algorithmic psychosis induction (recommendation weaponization)

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Cognitive/Psychotic NISS 8.1 indirect

QIF-T0066

Slow drift / boiling frog (adiabatic phase space manipulation)

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 7.4 direct

QIF-T0067

Phase dynamics replay/mimicry (GAN-synthesized or RF-injected neural trajectories)

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Mood/Trauma NISS 6 direct

QIF-T0068

Bifurcation forcing (critical parameter manipulation to trigger neural state transitions)

Pathway: N5 (striatum/STN) → motor selection; N4 (thalamus/hypothalamus) → sensory gating

Motor/Neurocognitive NISS 8.1 direct

QIF-T0069

Separatrix leakage (meta-biometric extraction from dynamical transition observations)

Pathway: N7 (PFC/M1) → executive function; N6 (hippocampus/amygdala) → emotion regulation

Cognitive/Psychotic NISS 2.7 direct

QIF-T0070

Integrator/resonator type switching (tonic excitability manipulation)

Pathway: N4 (thalamus/hypothalamus) → sensory gating; N3 (cerebellar cortex/deep cerebellar nuclei) → motor coordination

Motor/Neurocognitive NISS 7.4 direct

QIF-T0073

Neurotransmitter	Class	Synth Steps	Receptors	Cofactors	Key Enzymes	QIF Bands
Dopamine (DA)	catecholamine	3	5	5	PAH, TH, DDC	N5N6N7
Serotonin (5-HT)	indolamine	2	8	5	TPH1 (peripheral) / TPH2 (brain), DDC	N2N6N7
Norepinephrine (NE)	catecholamine	1	4	5	DBH	N2N6N7
Acetylcholine (ACh)	acetylcholine	1	7	3	CHAT	N2N4N6N7
Glutamate (Glu)	amino_acid	2	6	4	GLS / GLS2, GLUD1 / various aminotransferases	N1N2N3N4
Gamma-Aminobutyric Acid (GABA)	amino_acid	1	2	2	GAD1 (GAD67) / GAD2 (GAD65)	N1N2N3N4
Glycine (Gly)	amino_acid	1	2	2	SHMT1 / SHMT2	N1N2
Histamine (HA)	monoamine	1	4	1	HDC	N4
Endorphins / Enkephalins / Dynorphins (Endogenous Opioids)	peptide	3	4	1	PCSK1 (PC1), PCSK2 (PC2)	N2N4N5N6
Substance P (SP)	peptide	1	1	0	—	N1N2N6
Orexin / Hypocretin (OX)	peptide	1	2	0	—	N4
Oxytocin (OT)	peptide	1	1	0	—	N4N6
Vasopressin (ADH) (AVP)	peptide	1	3	0	—	N4
Nitric Oxide (NO)	gas	1	1	4	NOS1 (nNOS, neuronal) / NOS3 (eNOS, endothelial) / NOS2 (iNOS, inducible)	N1N2N3N4
Endocannabinoids (eCB)	lipid	2	2	0	NAPEPLD, DAGLA / DAGLB	N3N5N6N7
Adenosine / ATP (Purinergic) (Ado/ATP)	purine	2	3	0	—	N2N3N4N5
Neuropeptide Y (NPY)	peptide	1	3	0	—	N4N6N7
Epinephrine (Epi)	catecholamine	1	4	0	PNMT	N2

Domain	Electrical Stim.	Magnetic Stim.	Neurofeedback	Signal Dx & Recording	Sensory Prosthetics	BCI & Interfaces
Movement & Motor	8 13 4 tDCS/tACS neuromodulation QIF-T0001 Deep brain stimulation (DBS) / Responsive neurostimulation (RNS) QIF-T0002 Adaptive stimulation protocol adjustment in closed-loop BCIs QIF-T0007 Thermal ablation (stereotactic radiosurgery, LITT, RF ablation) QIF-T0015 Closed-loop responsive neurostimulation (RNS) QIF-T0023 High-frequency stimulation for neural suppression (DBS at >100 Hz) QIF-T0029 Functional electrical stimulation (FES) / brain-controlled prosthetics QIF-T0030 Responsive neurostimulation at seizure bifurcation (RNS/NeuroPace) QIF-T0068 Temporal interference (TI) deep brain stimulation QIF-T0011 Temporal interference (TI) non-invasive deep brain stimulation QIF-T0013 Selective neural signal routing in closed-loop therapy QIF-T0028 Stochastic resonance (SR) — adding noise to enhance weak signal detection QIF-T0063 Slow DBS parameter optimization (adiabatic adjustment protocols) QIF-T0066 Sensor fusion for motor disorder assessment and digital biomarker collection QIF-T0101 Galvanic vestibular stimulation (GVS) therapy QIF-T0111 Transcranial direct current stimulation (tDCS) long-term protocols QIF-T0115 Motor cortex rTMS / tDCS for stroke rehabilitation QIF-T0123 Connectome-informed DBS targeting / network-level stimulation QIF-T0135 Transcranial photobiomodulation for Parkinson's disease neuroprotection QIF-T0136 Anodal tDCS for stroke motor rehab, depression QIF-T0145 Gamma-tACS for Parkinson's motor restoration QIF-T0146 Deep brain optogenetic stimulation for Parkinson's disease QIF-T0137 Non-genetic deep brain photovoltaic stimulation QIF-T0138 Wireless photothermal deep brain stimulation QIF-T0139 Magnetothermal deep brain stimulation for Parkinson's QIF-T0141	1 rTMS of Broca's area for post-stroke aphasia rehabilitation QIF-T0118	1 3 Motor learning and neural rehabilitation (learned pathway strengthening) QIF-T0059 Signal routing in closed-loop neuroprosthetics QIF-T0004 Neurofeedback for self-regulation / agency restoration post-stroke QIF-T0037 Adaptive BCI calibration for patients with changing neural dynamics QIF-T0058	4 Gait analysis for rehabilitation and neurological monitoring QIF-T0088 Remote Parkinson's monitoring and neurological screening QIF-T0089 Contactless vital sign monitoring for sleep studies, elder care, and post-surgical recovery QIF-T0090 Diagnostic SICI for ALS, stroke biomarker QIF-T0142	1 Speech neuroprosthesis / brain-to-speech BCI QIF-T0131	2 BCI command interfaces for motor-impaired patients QIF-T0008 P300 BCI (communication for locked-in patients) QIF-T0035
Seizure & Epilepsy	5 4 Deep brain stimulation (DBS) / Responsive neurostimulation (RNS) QIF-T0002 Adaptive stimulation protocol adjustment in closed-loop BCIs QIF-T0007 Thermal ablation (stereotactic radiosurgery, LITT, RF ablation) QIF-T0015 Closed-loop responsive neurostimulation (RNS) QIF-T0023 Responsive neurostimulation at seizure bifurcation (RNS/NeuroPace) QIF-T0068 Selective neural signal routing in closed-loop therapy QIF-T0028 Brain state detection for seizure prediction (transition pattern monitoring) QIF-T0069 Excitability modulation in epilepsy and pain management QIF-T0070 In-ear EEG for seizure detection, sleep staging, cognitive monitoring QIF-T0073	—	—	4 1 EEG/ECoG diagnostic monitoring QIF-T0003 Brain mapping for surgical planning / functional localization QIF-T0027 Continuous EEG monitoring (epilepsy, ICU) QIF-T0056 Brain network analysis for diagnosis and surgical planning QIF-T0057 Integrated hearing health + cognitive monitoring earbuds QIF-T0095	—	—
Mood & Affective	5 11 3 tDCS/tACS neuromodulation QIF-T0001 Deep brain stimulation (DBS) / Responsive neurostimulation (RNS) QIF-T0002 Repetitive transcranial magnetic stimulation (rTMS) QIF-T0009 Electroconvulsive therapy (ECT) QIF-T0026 ECT (electroconvulsive therapy) / TMS for treatment-resistant depression QIF-T0124 Temporal interference (TI) deep brain stimulation QIF-T0011 Temporal interference (TI) non-invasive deep brain stimulation QIF-T0013 Neuroplasticity-based rehabilitation / personality change monitoring in DBS QIF-T0033 Slow DBS parameter optimization (adiabatic adjustment protocols) QIF-T0066 Sensor fusion for motor disorder assessment and digital biomarker collection QIF-T0101 Deep brain stimulation of nucleus accumbens / ventral capsule QIF-T0116 Closed-loop auditory stimulation for slow-wave sleep enhancement QIF-T0121 DBS of amygdala / extinction learning facilitation QIF-T0127 DBS of subcallosal cingulate / ventral capsule for depression QIF-T0128 Connectome-informed DBS targeting / network-level stimulation QIF-T0135 Anodal tDCS for stroke motor rehab, depression QIF-T0145 Deep brain optogenetic stimulation for Parkinson's disease QIF-T0137 Non-genetic deep brain photovoltaic stimulation QIF-T0138 Electroacupuncture for depression, chronic pain QIF-T0156	—	2 6 Neurofeedback therapy QIF-T0022 Longitudinal EEG monitoring for neurofeedback and cognitive rehabilitation QIF-T0074 Audio-visual entrainment (AVE) / photic driving therapy QIF-T0010 Neurofeedback for self-regulation / agency restoration post-stroke QIF-T0037 Memory retrieval and consolidation enhancement therapy QIF-T0054 Memory consolidation enhancement (targeted memory reactivation during sleep) QIF-T0060 Targeted memory reactivation (TMR) / sleep-dependent memory consolidation research QIF-T0117 Neurofeedback training for emotional regulation QIF-T0119	3 4 EEG-based cognitive and psychiatric assessment QIF-T0041 Auditory brainstem response (ABR) audiometry, ASSR-based hearing threshold estimation, tinnitus masking therapy QIF-T0100 Photoplethysmography (PPG) via screen light for contactless vital sign monitoring QIF-T0102 Contactless vital sign monitoring for telemedicine and patient screening QIF-T0084 Contactless vital sign monitoring for sleep studies, elder care, and post-surgical recovery QIF-T0090 Thermal imaging for pain assessment and autonomic function testing QIF-T0092 ERP/EEG biomarker tracking for treatment response monitoring QIF-T0125	—	—
Cognitive & Neurodevelopmental	1 11 Thermal ablation (stereotactic radiosurgery, LITT, RF ablation) QIF-T0015 tACS with carrier-envelope paradigm QIF-T0014 Neuroplasticity-based rehabilitation / personality change monitoring in DBS QIF-T0033 Working memory training / tDCS-enhanced cognitive training QIF-T0034 Brain state detection for seizure prediction (transition pattern monitoring) QIF-T0069 In-ear EEG for seizure detection, sleep staging, cognitive monitoring QIF-T0073 Sensor fusion for motor disorder assessment and digital biomarker collection QIF-T0101 Transcranial direct current stimulation (tDCS) long-term protocols QIF-T0115 Closed-loop auditory stimulation for slow-wave sleep enhancement QIF-T0121 Transcranial photobiomodulation for Parkinson's disease neuroprotection QIF-T0136 Anodal tDCS for stroke motor rehab, depression QIF-T0145 Gamma-tACS for Parkinson's motor restoration QIF-T0146	1 2 1 TMS (cortical suppression / virtual lesion technique) QIF-T0025 TMS of temporoparietal junction for social cognition research QIF-T0130 rTMS of Wernicke's area for tinnitus / auditory hallucinations QIF-T0132 TMS-EEG biomarker for Alzheimer's cholinergic deficit QIF-T0151	3 6 Neurofeedback therapy QIF-T0022 Brain-state dependent therapy timing QIF-T0053 Longitudinal EEG monitoring for neurofeedback and cognitive rehabilitation QIF-T0074 Audio-visual entrainment (AVE) / photic driving therapy QIF-T0010 Neurofeedback for self-regulation / agency restoration post-stroke QIF-T0037 Memory retrieval and consolidation enhancement therapy QIF-T0054 Memory consolidation enhancement (targeted memory reactivation during sleep) QIF-T0060 Coherence-based neurofeedback (SMR/beta coherence training) QIF-T0061 Targeted memory reactivation (TMR) / sleep-dependent memory consolidation research QIF-T0117	6 4 2 EEG/ECoG diagnostic monitoring QIF-T0003 Brain mapping for surgical planning / functional localization QIF-T0027 EEG-based cognitive and psychiatric assessment QIF-T0041 ERP-based clinical diagnostics QIF-T0052 Brain network analysis for diagnosis and surgical planning QIF-T0057 Eye tracking for neurological assessment and cognitive rehabilitation QIF-T0085 Subliminal priming research / implicit cognitive assessment QIF-T0040 Integrated hearing health + cognitive monitoring earbuds QIF-T0095 Pre-surgical neurological baseline assessment for BCI implant calibration QIF-T0099 ERP/EEG biomarker tracking for treatment response monitoring QIF-T0125 Ambient assisted living for elderly monitoring QIF-T0098 EEG pharmacodynamic biomarker monitoring QIF-T0153	—	1 1 High-frequency SSVEP-based BCI for locked-in patients QIF-T0103 UX design for cognitive accessibility in medical BCIs QIF-T0064
Pain & Somatosensory	3 6 2 tDCS/tACS neuromodulation QIF-T0001 Repetitive transcranial magnetic stimulation (rTMS) QIF-T0009 Closed-loop responsive neurostimulation (RNS) QIF-T0023 tACS with carrier-envelope paradigm QIF-T0014 Slow DBS parameter optimization (adiabatic adjustment protocols) QIF-T0066 Excitability modulation in epilepsy and pain management QIF-T0070 Transcranial direct current stimulation (tDCS) long-term protocols QIF-T0115 Motor cortex rTMS / tDCS for stroke rehabilitation QIF-T0123 Optical cochlear implant, infrared nerve stimulation QIF-T0140 Electroacupuncture for depression, chronic pain QIF-T0156 CSD as migraine intervention target; ECT therapeutic mechanism QIF-T0161	1 rTMS of Wernicke's area for tinnitus / auditory hallucinations QIF-T0132	—	1 2 Auditory brainstem response (ABR) audiometry, ASSR-based hearing threshold estimation, tinnitus masking therapy QIF-T0100 Contactless vital sign monitoring for telemedicine and patient screening QIF-T0084 Thermal imaging for pain assessment and autonomic function testing QIF-T0092	2 1 Sensory prosthetics (cochlear implants, retinal prostheses, somatosensory feedback) QIF-T0067 Cochlear implant therapy QIF-T0134 Visual cortex prosthesis (Orion / Second Sight) / phosphene mapping QIF-T0133	—
Sleep & Circadian	4 tACS with carrier-envelope paradigm QIF-T0014 Brain state detection for seizure prediction (transition pattern monitoring) QIF-T0069 In-ear EEG for seizure detection, sleep staging, cognitive monitoring QIF-T0073 Closed-loop auditory stimulation for slow-wave sleep enhancement QIF-T0121	—	1 Audio-visual entrainment (AVE) / photic driving therapy QIF-T0010	5 3 EEG/ECoG diagnostic monitoring QIF-T0003 EEG-based cognitive and psychiatric assessment QIF-T0041 Contactless vital sign monitoring for sleep studies and elder care QIF-T0075 PPG-based cardiovascular health monitoring QIF-T0093 Auditory brainstem response (ABR) audiometry, ASSR-based hearing threshold estimation, tinnitus masking therapy QIF-T0100 Laser Doppler vibrometry for contactless cardiac monitoring QIF-T0078 Contactless vital sign monitoring for sleep studies, elder care, and post-surgical recovery QIF-T0090 Multi-device remote patient monitoring for chronic disease management QIF-T0097	—	—
Communication & Rehab	2 Selective neural signal routing in closed-loop therapy QIF-T0028 Motor cortex rTMS / tDCS for stroke rehabilitation QIF-T0123	2 rTMS of Broca's area for post-stroke aphasia rehabilitation QIF-T0118 rTMS of Wernicke's area for tinnitus / auditory hallucinations QIF-T0132	1 1 Motor learning and neural rehabilitation (learned pathway strengthening) QIF-T0059 Adaptive baseline recalibration for changing patient conditions QIF-T0071	1 2 Auditory brainstem response (ABR) audiometry, ASSR-based hearing threshold estimation, tinnitus masking therapy QIF-T0100 Contactless vital sign monitoring for telemedicine and patient screening QIF-T0084 Diagnostic SICI for ALS, stroke biomarker QIF-T0142	2 Speech neuroprosthetics (neural speech decoding) QIF-T0036 Speech neuroprosthesis / brain-to-speech BCI QIF-T0131	3 BCI command interfaces for motor-impaired patients QIF-T0008 P300 BCI (communication for locked-in patients) QIF-T0035 High-frequency SSVEP-based BCI for locked-in patients QIF-T0103

Clinical Outcome References for Threat Modeling.

For Clinicians

Diagnostic Clusters

Risk Classification

Evidence Confidence

Diagnosis Explorer

The Neural Impact Chain

All 76 Techniques by Cluster

Same Mechanism. Two Outcomes.

Why This Matters

FDA Status Breakdown

Dual-Use Classification

Clinical Domains

Movement & Motor

Seizure & Epilepsy

Mood & Affective

Cognitive & Neurodevelopmental

Pain & Somatosensory

Sleep & Circadian

Communication & Rehab

Explore by Domain × Modality

Conditions Treated

All 130 Therapeutic Analogs

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Clinical Outcome References
for Threat Modeling.