QIF-T0156

medium

High-frequency electroacupuncture dorsal raphe serotonin drive (100Hz peripheral afferent)

Tier 2 — Validated (Independently Replicated)

Legacy status: CONFIRMED

Technique Details

Tactic: QIF-N.MD
Status: CONFIRMED
Bands: I0, N1, N2, N3, N4, N5

✚ Therapeutic Application

100Hz electroacupuncture (ST36/SP6, 1-2mA, 0.2ms pulse, 45min) selectively activates serotonergic DRN neurons. pCPA (5-HT synthesis blocker) abolishes effect, confirming serotonin necessity (Lin 2017). Frequency-selective: 100Hz=5-HT (DRN), 2Hz=opioid (enkephalin). Second mechanism: 2Hz at GV20/GV29 downregulates miRNA-16 -> reduces SERT -> increases synaptic 5-HT (Zhao 2019). Peripheral needle -> spinal -> brainstem pathway.

Clinical Analog

Electroacupuncture for depression, chronic pain

Treats

depression
chronic pain
pain-depression comorbidity

Neural Impact

6 of 7 neural bands affected

I0 N1 N2 N3 N4 N5

Drag to rotate. Click a region to learn more.

Click or hover over a glowing region to see the attack techniques targeting it and their severity.

Scoring

NISS v1.1

0.0None

Validation Status

Theoretical / Not yet validated. This technique has not been independently tested. See the validation dashboard for what has been tested.

Qinnovate Neural Security Atlas Edit this on GitHub