QIF-T0150

medium

Transcutaneous auricular VNS (tVNS) cholinergic modulation

Tier 3 — Demonstrated (Lab-proven)

Legacy status: DEMONSTRATED

Technique Details

Tactic: QIF-E.RD
Status: DEMONSTRATED
Bands: I0, N1

✚ Therapeutic Application

Transcutaneous electrical stimulation of auricular branch of vagus nerve (ABVN) at cymba conchae (100% ABVN innervation). Activates NTS -> cholinergic relay. EEG microstate changes confirmed. P300 modulation demonstrated. Peripheral: alpha7 nAChR anti-inflammatory pathway. No surgery. Wearable ear clip (CE-marked Nemos).

Clinical Analog

tVNS for epilepsy, depression, Alzheimer's

Treats

epilepsy
depression
Alzheimer's disease
PTSD

Neural Impact

2 of 7 neural bands affected

I0 N1

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Scoring

NISS v1.1

0.0None

Validation Status

Theoretical / Not yet validated. This technique has not been independently tested. See the validation dashboard for what has been tested.

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