QIF-T0158
highSilent excitatory/inhibitory ratio manipulation (sub-threshold seizure priming)
Tier 5 — Theoretical (Modeled / Simulated)
Legacy status: THEORETICAL
Technique Details
- Tactic
- QIF-P.DS
- Status
- THEORETICAL
- Bands
- I0, N1, N2
✚ Therapeutic Application
Sub-threshold anodal tDCS (1-2mA, repeated sessions over weeks) drives polarity-dependent shift: GABA down 10-30%, Glu up (dose-dependent). Net: progressive seizure threshold reduction without acute clinical presentation. Attack completed by separate trigger event. Distinct from T0122 (kindling: implanted electrodes, amygdala) and T0026/T0029 (acute superthreshold). Operates sub-threshold, non-invasive, preparatory not direct.
Clinical Analog
tDCS research (same parameters, different intent)
Treats
- research tool
Neural Impact
3 of 7 neural bands affected
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Scoring
Validation Status
Theoretical / Not yet validated. This technique has not been independently tested. See the validation dashboard for what has been tested.