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QIF-T0136

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Transcranial photobiomodulation (670/808nm)

Tier 2 — Validated (Independently Replicated)

Legacy status: CONFIRMED

Technique Details

Tactic
QIF-E.RD
Status
CONFIRMED
Bands
I0, N1

Therapeutic Application

Propagating NIR photons (670/808nm) absorbed by mitochondrial cytochrome c oxidase (CCO) in dopaminergic neurons. CCO activation increases ATP production, upregulates tyrosine hydroxylase (TH) and VMAT2 expression over days-weeks. Neuroprotective, not acutely stimulatory. Requires cofactor readiness (Fe2+, BH4, B6).

Clinical Analog

Transcranial photobiomodulation for Parkinson's disease neuroprotection

Treats

  • Parkinson's disease
  • neurodegeneration
  • traumatic brain injury

Neural Impact

2 of 7 neural bands affected

I0 N1

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Scoring

NISS v1.1
0.0None

Validation Status

Theoretical / Not yet validated. This technique has not been independently tested. See the validation dashboard for what has been tested.

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