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Severity
Status
Bands
Category
Showing 161 of 161 techniques
IDTechnique / AnalogSeverityStatusNISSBands
QIF-T0001
Signal injection
tDCS/tACS neuromodulation
highCONFIRMED6.1I0N1
QIF-T0002
Neural ransomware
Deep brain stimulation (DBS) / Responsive neurostimulation (RNS)
criticalEMERGING6.1N3N7N6
QIF-T0003
Eavesdropping / signal interception
EEG/ECoG diagnostic monitoring
highCONFIRMED2.7I0N1S1S2S3
QIF-T0004
Man-in-the-middle
Signal routing in closed-loop neuroprosthetics
criticalDEMONSTRATED2.7I0S1S2
QIF-T0005
Quantum tunneling exploit
Quantum sensing for neural diagnostics (NV-center magnetometry)
highTHEORETICAL6.1I0N1
QIF-T0006
Davydov soliton attack
Biophoton/soliton-based cellular signaling research
highTHEORETICAL6.1I0N1
QIF-T0007
Protocol manipulation
Adaptive stimulation protocol adjustment in closed-loop BCIs
mediumDEMONSTRATED4.1S1S2
QIF-T0008
Command hijacking
BCI command interfaces for motor-impaired patients
highTHEORETICAL6.1S2N7N6N5
QIF-T0009
RF false brainwave injection
Repetitive transcranial magnetic stimulation (rTMS)
highEMERGING7.4S1S2N4N5N6N7
QIF-T0010
ELF neural entrainment
Audio-visual entrainment (AVE) / photic driving therapy
criticalCONFIRMED7.4S1N4N5N6N7
QIF-T0011
Intermodulation (BCI signal weaponized)
Temporal interference (TI) deep brain stimulation
criticalTHEORETICAL7.4S2N4N5N6
QIF-T0012
Pulsed microwave (Frey effect)
Transcranial microwave stimulation (experimental)
highCONFIRMED5.4S3N2N7
QIF-T0013
Temporal interference (deep targeting)
Temporal interference (TI) non-invasive deep brain stimulation
highDEMONSTRATED7.4S2N4N5N6
QIF-T0014
Envelope modulation (stealth carrier)
tACS with carrier-envelope paradigm
highDEMONSTRATED8.1S1S2N1N2N3N4N5N6N7
QIF-T0015
Directed energy (thermal I0 damage)
Thermal ablation (stereotactic radiosurgery, LITT, RF ablation)
criticalCONFIRMED5.4S3I0
QIF-T0016
Professor X backdoor (training-time)
Professor X backdoor (training-time)
highDEMONSTRATED6.0S2
QIF-T0017
Transfer learning backdoor
Transfer learning backdoor
highDEMONSTRATED6.0S2
QIF-T0018
Adversarial filter attack
Adversarial filter attack
mediumDEMONSTRATED5.4S1S2
QIF-T0019
Universal adversarial perturbation (UAP)
Universal adversarial perturbation (UAP)
mediumDEMONSTRATED5.4S1S2
QIF-T0020
Membership inference on neural data
Clinical trial participation verification
mediumEMERGING2.7S2S3
QIF-T0021
Federated gradient leakage
Federated learning for multi-site clinical BCI trials
mediumEMERGING2.7S2S3
QIF-T0022
Neurofeedback falsification
Neurofeedback therapy
highEMERGING8.1S2N7
QIF-T0023
Closed-loop perturbation cascade
Closed-loop responsive neurostimulation (RNS)
criticalTHEORETICAL7.4S2I0N5N6N7
QIF-T0024
Training data poisoning (model bias injection)
Training data poisoning (model bias injection)
highDEMONSTRATED6.0S2
QIF-T0025
Neuronal jamming
TMS (cortical suppression / virtual lesion technique)
highDEMONSTRATED5.4I0N2N3N4N5N6N7
QIF-T0026
Neuronal flooding
Electroconvulsive therapy (ECT)
criticalTHEORETICAL6.1I0N4N5N6N7
QIF-T0027
Neuronal scanning
Brain mapping for surgical planning / functional localization
mediumTHEORETICAL3.4I0N4N5N6N7
QIF-T0028
Neural selective forwarding
Selective neural signal routing in closed-loop therapy
highTHEORETICAL6.1I0S1
QIF-T0029
Neural DoS (stimulation flood)
High-frequency stimulation for neural suppression (DBS at >100 Hz)
highDEMONSTRATED6.1I0N4N5N6N7
QIF-T0030
Motor hijacking
Functional electrical stimulation (FES) / brain-controlled prosthetics
criticalTHEORETICAL6.7I0N5N6N7
QIF-T0031
Battery drain attack (resource depletion)
Battery drain attack (resource depletion)
mediumTHEORETICAL0.7S1S2
QIF-T0032
Identity spoofing (neural biometric)
Neural biometric authentication for medical device access
highEMERGING2.7N3N7N6
QIF-T0033
Identity erosion (long-term personality drift)
Neuroplasticity-based rehabilitation / personality change monitoring in DBS
criticalTHEORETICAL8.0N6N7
QIF-T0034
Working memory poisoning
Working memory training / tDCS-enhanced cognitive training
highTHEORETICAL5.4N6N7
QIF-T0035
P300 interrogation
P300 BCI (communication for locked-in patients)
highDEMONSTRATED2.7N7
QIF-T0036
Thought decoding (covert speech)
Speech neuroprosthetics (neural speech decoding)
criticalEMERGING3.4N7
QIF-T0037
Agency manipulation
Neurofeedback for self-regulation / agency restoration post-stroke
criticalTHEORETICAL7.4N5N6N7
QIF-T0038
Brainprint theft
Brain fingerprinting / neural identity verification
highEMERGING4.7N6N7
QIF-T0039
Self-model corruption
Psychedelic-assisted therapy (controlled self-model disruption); rubber hand illusion research
criticalTHEORETICAL8.0N6N7
QIF-T0040
Neurophishing
Subliminal priming research / implicit cognitive assessment
highEMERGING5.4S3N7
QIF-T0041
Cognitive biometric inference
EEG-based cognitive and psychiatric assessment
highDEMONSTRATED2.7N6N7S3
QIF-T0042
BLE/RF side-channel
BLE/RF side-channel
mediumCONFIRMED2.7S1S2
QIF-T0043
Supply chain compromise (firmware backdoor)
Supply chain compromise (firmware backdoor)
highCONFIRMED4.7S2S3
QIF-T0044
Cloud infrastructure attack
Cloud infrastructure attack
mediumCONFIRMED2.7S3
QIF-T0045
Harvest-now-decrypt-later
Harvest-now-decrypt-later
criticalCONFIRMED2.7S3
QIF-T0046
OTA firmware weaponization
OTA firmware weaponization
highEMERGING6.7S2S3
QIF-T0047
Mass BCI compromise (platform attack)
Mass BCI compromise (platform attack)
criticalEMERGING6.1S2S3
QIF-T0048
Electrode compromise (physical tamper)
Electrode compromise (physical tamper)
highDEMONSTRATED6.1I0
QIF-T0049
Wireless authentication bypass
Wireless authentication bypass
highCONFIRMED0.7S2S3
QIF-T0050
Hardware fault injection (voltage/EM glitching)
Hardware fault injection (voltage/EM glitching)
highDEMONSTRATED3.4S1S2
QIF-T0051
Neural data privacy breach
Clinical neural data management for treatment optimization
highCONFIRMED2.0N1S1S2S3
QIF-T0052
ERP harvesting
ERP-based clinical diagnostics
highDEMONSTRATED2.7N6N7
QIF-T0053
Cognitive state capture
Brain-state dependent therapy timing
highCONFIRMED2.7N6N7
QIF-T0054
Memory extraction
Memory retrieval and consolidation enhancement therapy
criticalTHEORETICAL3.4N6N7
QIF-T0055
BCI cognitive warfare
BCI cognitive warfare
criticalTHEORETICAL8.1S3N4N5N6N7
QIF-T0056
Neuro-surveillance
Continuous EEG monitoring (epilepsy, ICU)
highEMERGING2.7N6N7S3
QIF-T0057
Network mapping (BCI topology)
Brain network analysis for diagnosis and surgical planning
lowCONFIRMED0.0S2S3
QIF-T0058
Calibration poisoning
Adaptive BCI calibration for patients with changing neural dynamics
highDEMONSTRATED6.0S1S2
QIF-T0059
Pattern lock (learned pathway persistence)
Motor learning and neural rehabilitation (learned pathway strengthening)
mediumTHEORETICAL7.4S1S2N7
QIF-T0060
Memory implant (cross-session persistence)
Memory consolidation enhancement (targeted memory reactivation during sleep)
highTHEORETICAL7.4N6N7
QIF-T0061
Coherence mimicry
Coherence-based neurofeedback (SMR/beta coherence training)
highTHEORETICAL0.7I0S1
QIF-T0062
Gradual drift (slow parameter shift)
Gradual dose titration in neurostimulation therapy
mediumTHEORETICAL7.4S1N7
QIF-T0063
Noise injection (detection masking)
Stochastic resonance (SR) — adding noise to enhance weak signal detection
mediumTHEORETICAL1.4I0S1
QIF-T0064
User consent fatigue (neural permission flooding)
UX design for cognitive accessibility in medical BCIs
mediumEMERGING4.7S2S3N7
QIF-T0065
Algorithmic psychosis induction (recommendation weaponization)
Therapeutic content recommendation for mental health
criticalCONFIRMED8.1S3S2N5N6N7
QIF-T0066
Slow drift / boiling frog (adiabatic phase space manipulation)
Slow DBS parameter optimization (adiabatic adjustment protocols)
highTHEORETICAL7.4I0N1N2N3N4N5N6N7
QIF-T0067
Phase dynamics replay/mimicry (GAN-synthesized or RF-injected neural trajectories)
Sensory prosthetics (cochlear implants, retinal prostheses, somatosensory feedback)
criticalDEMONSTRATED6.0S1I0N1N3N5N6N7
QIF-T0068
Bifurcation forcing (critical parameter manipulation to trigger neural state transitions)
Responsive neurostimulation at seizure bifurcation (RNS/NeuroPace)
criticalEMERGING8.1I0N1N2N3N4N5
QIF-T0069
Separatrix leakage (meta-biometric extraction from dynamical transition observations)
Brain state detection for seizure prediction (transition pattern monitoring)
highTHEORETICAL2.7N3N4N5N6N7I0S1
QIF-T0070
Integrator/resonator type switching (tonic excitability manipulation)
Excitability modulation in epilepsy and pain management
highTHEORETICAL7.4I0N1N2N3N4
QIF-T0071
Baseline adaptation poisoning (re-enrollment window exploitation)
Adaptive baseline recalibration for changing patient conditions
highEMERGING7.4S1S2I0
QIF-T0072
Transducer inversion (acoustic eavesdropping via speaker-to-microphone reprogramming)
Transducer inversion (acoustic eavesdropping via speaker-to-microphone reprogramming)
highCONFIRMED2.0S1S2S3
QIF-T0073
Ear-canal neural eavesdropping via modified consumer earbud (supply chain in-ear EEG)
In-ear EEG for seizure detection, sleep staging, cognitive monitoring
criticalEMERGING2.7S1I0N1N2N3
QIF-T0074
Cognitive inference from longitudinal in-ear EEG (personalized cognitive profiling)
Longitudinal EEG monitoring for neurofeedback and cognitive rehabilitation
criticalEMERGING4.0N3N4N5N6N7S2S3
QIF-T0075
Ultrasonic sonar vital sign extraction (inaudible Doppler physiological sensing)
Contactless vital sign monitoring for sleep studies and elder care
highDEMONSTRATED1.4S1S2S3
QIF-T0076
Haptic motor body sonar (taptic engine repurposing for tissue impedance profiling)
Acoustic impedance spectroscopy for body composition and edema monitoring
mediumTHEORETICAL1.4S1S2
QIF-T0077
IR vascular mapping via Face ID system (NIR hemoglobin absorption imaging)
Near-infrared spectroscopy (NIRS) for cerebral and peripheral vascular imaging
highEMERGING2.0S1S2S3
QIF-T0078
LiDAR remote pulse detection (laser Doppler vibrometry for cardiac waveform extraction)
Laser Doppler vibrometry for contactless cardiac monitoring
highTHEORETICAL1.4S1S2S3
QIF-T0079
Ear canal acoustic fingerprinting (ANC echo profiling for covert identification)
Ear canal acoustic authentication for medical device access control
highDEMONSTRATED2.0S1S2S3
QIF-T0080
Gyroscope acoustic eavesdropping (MEMS speech capture via resonant frequency aliasing)
Gyroscope acoustic eavesdropping (MEMS speech capture via resonant frequency aliasing)
highDEMONSTRATED1.4S1S2S3
QIF-T0081
Accelerometer speech reconstruction (vibration-to-audio via surface-coupled MEMS)
Accelerometer speech reconstruction (vibration-to-audio via surface-coupled MEMS)
highDEMONSTRATED1.4S1S2S3
QIF-T0082
Ultrasonic cross-device tracking (inaudible beacon correlation for user identification)
Ultrasonic cross-device tracking (inaudible beacon correlation for user identification)
highCONFIRMED2.0S1S2S3
QIF-T0083
Acoustic keystroke inference (typing sound classification for credential extraction)
Acoustic keystroke inference (typing sound classification for credential extraction)
highCONFIRMED2.0S1S2S3
QIF-T0084
Remote photoplethysmography (camera-based pulse and blood oxygen extraction)
Contactless vital sign monitoring for telemedicine and patient screening
highDEMONSTRATED1.4S1S2S3
QIF-T0085
Eye tracking cognitive state inference (gaze pattern analysis for attention and intent profiling)
Eye tracking for neurological assessment and cognitive rehabilitation
criticalDEMONSTRATED3.4S1S2N3N7
QIF-T0086
Ambient light sensor side-channel exfiltration (screen content inference via reflected light)
Ambient light sensor side-channel exfiltration (screen content inference via reflected light)
mediumDEMONSTRATED0.7S1S2S3
QIF-T0087
Accelerometer keystroke inference (touchscreen tap localization for PIN/password recovery)
Accelerometer keystroke inference (touchscreen tap localization for PIN/password recovery)
highCONFIRMED2.0S1S2S3
QIF-T0088
Gait biometric identification (IMU-based walking pattern fingerprint for persistent tracking)
Gait analysis for rehabilitation and neurological monitoring
highCONFIRMED2.0S1S2S3
QIF-T0089
Tremor and movement neurological profiling (IMU-based motor disorder detection and health inference)
Remote Parkinson's monitoring and neurological screening
criticalDEMONSTRATED2.7S1S2N1N7
QIF-T0090
WiFi CSI passive body sensing (through-wall vital signs, 3D pose reconstruction, respiratory and gait biometric inference via dedicated or commodity WiFi hardware)
Contactless vital sign monitoring for sleep studies, elder care, and post-surgical recovery
criticalDEMONSTRATED2.0S1S2S3
QIF-T0091
BLE physical-layer device fingerprinting (radio frequency imperfection tracking)
BLE physical-layer device fingerprinting (radio frequency imperfection tracking)
highDEMONSTRATED2.0S1S2S3
QIF-T0092
Thermal facial stress and emotion inference (IR thermography for autonomic nervous system state extraction)
Thermal imaging for pain assessment and autonomic function testing
highDEMONSTRATED2.0S1S2N7
QIF-T0093
PPG pulse waveform biometric identification (cardiac signature fingerprinting via wearable optical sensor)
PPG-based cardiovascular health monitoring
highDEMONSTRATED2.0S1S2S3
QIF-T0094
Magnetometer speaker-leakage eavesdropping (magnetic field emanation capture from speaker voice coils)
Magnetometer speaker-leakage eavesdropping (magnetic field emanation capture from speaker voice coils)
highDEMONSTRATED1.4S1S2S3
QIF-T0095
Acoustic-to-neural profiling pipeline (consumer earbud escalation from audio to cognitive exploitation)
Integrated hearing health + cognitive monitoring earbuds
criticalEMERGING4.0S1S2S3I0N1N7
QIF-T0096
Multi-modal biometric fusion attack (cross-sensor identity correlation for persistent tracking)
Multi-modal patient identification for medication safety
criticalEMERGING2.0S1S2S3
QIF-T0097
Cross-device physiological correlation (phone + watch + earbuds comprehensive health profiling)
Multi-device remote patient monitoring for chronic disease management
criticalTHEORETICAL2.7S1S2S3N7
QIF-T0098
WiFi + camera passive surveillance fusion (through-wall presence detection with visual identification)
Ambient assisted living for elderly monitoring
criticalEMERGING2.0S1S2S3
QIF-T0099
Consumer-sensor-to-BCI kill chain escalation (pre-implant reconnaissance and cognitive priming via consumer devices)
Pre-surgical neurological baseline assessment for BCI implant calibration
criticalTHEORETICAL4.7S1S2S3I0N1N7
QIF-T0100
Neural steganographic encoding (inaudible audio watermarking for covert neural command/biofingerprint channel)
Auditory brainstem response (ABR) audiometry, ASSR-based hearing threshold estimation, tinnitus masking therapy
lowPLAUSIBLE1.4S3S1I0N1N4N7
QIF-T0101
Multi-modal keystroke inference via acoustic-optical-RF fusion (password/input recovery without mic/camera permissions)
Sensor fusion for motor disorder assessment and digital biomarker collection
mediumDEMONSTRATED1.4S3S2S1
QIF-T0102
Passive facial geometry estimation via display-as-illuminator inverse photometry (presence/orientation detection without camera)
Photoplethysmography (PPG) via screen light for contactless vital sign monitoring
lowSPECULATIVE0.7S3S2
QIF-T0103
SSVEP Frequency Hijack via Imperceptible Display Flicker
High-frequency SSVEP-based BCI for locked-in patients
highDEMONSTRATED6.0S3I0N7
QIF-T0104
Neural spoofing
Neural spoofing
highTHEORETICAL4.7I0N1
QIF-T0105
Neural sybil
Neural sybil
highTHEORETICAL4.7I0N1
QIF-T0106
Neural sinkhole
Neural sinkhole
highTHEORETICAL5.4I0N2
QIF-T0107
Neural nonce replay
Neural nonce replay
highTHEORETICAL5.4I0N1
QIF-T0108
Neuromorphic mimicry attack (synaptic weight tampering)
Neuromorphic mimicry attack (synaptic weight tampering)
highDEMONSTRATED4.7S1S2
QIF-T0109
Data alignment exploitation
Data alignment exploitation
mediumTHEORETICAL3.4S2I0
QIF-T0110
Vestibular balance profiling
Vestibular evoked myogenic potentials (VEMP) testing
mediumTHEORETICAL1.7I0
QIF-T0111
GVS motion illusion injection
Galvanic vestibular stimulation (GVS) therapy
mediumTHEORETICAL4.0I0N1N2N3N4
QIF-T0112
Vestibular-ocular reflex manipulation
VOR rehabilitation / caloric testing
mediumTHEORETICAL4.0I0N1N2N3
QIF-T0113
Cochlear-vestibular crosstalk exploitation
Bone-conducted vibration vestibular rehabilitation
mediumDEMONSTRATED4.0I0N1
QIF-T0114
Vestibular overload (vertigo induction)
Canalith repositioning (Epley maneuver) / vestibular habituation therapy
mediumTHEORETICAL5.4I0N1N2N3N4
QIF-T0115
Cumulative tissue excitability shift
Transcranial direct current stimulation (tDCS) long-term protocols
mediumTHEORETICAL5.7I0N1
QIF-T0116
Progressive reward pathway desensitization
Deep brain stimulation of nucleus accumbens / ventral capsule
mediumTHEORETICAL6.1N5N6
QIF-T0117
Incremental memory consolidation interference
Targeted memory reactivation (TMR) / sleep-dependent memory consolidation research
mediumTHEORETICAL5.4N6
QIF-T0118
Cumulative speech degradation
rTMS of Broca's area for post-stroke aphasia rehabilitation
mediumTHEORETICAL5.4N7
QIF-T0119
Delayed emotional baseline shift
Neurofeedback training for emotional regulation
mediumTHEORETICAL6.1N6
QIF-T0120
Latent cognitive decline via chronic electrode micromotion
Chronic DBS electrode maintenance / impedance management
mediumTHEORETICAL6.1I0N1N2N3N4N5N6N7
QIF-T0121
Sleep architecture manipulation
Closed-loop auditory stimulation for slow-wave sleep enhancement
mediumTHEORETICAL4.0N2N3N4
QIF-T0122
Chronic epileptogenic focus creation (kindling)
Kindling model in epilepsy research (preclinical)
mediumTHEORETICAL8.4N6
QIF-T0123
Structural motor pathway reorganization
Motor cortex rTMS / tDCS for stroke rehabilitation
mediumTHEORETICAL6.1N5N6N7
QIF-T0124
Autobiographical narrative coherence disruption
ECT (electroconvulsive therapy) / TMS for treatment-resistant depression
mediumTHEORETICAL6.4N6N7
QIF-T0125
Longitudinal neural fingerprint extraction
ERP/EEG biomarker tracking for treatment response monitoring
mediumTHEORETICAL2.7N7
QIF-T0126
Progressive visual response mapping
Visual evoked potential (VEP) diagnostics
mediumTHEORETICAL2.1N7
QIF-T0127
Acute fear circuit activation
DBS of amygdala / extinction learning facilitation
mediumTHEORETICAL4.0N6
QIF-T0128
Hedonic tone suppression
DBS of subcallosal cingulate / ventral capsule for depression
mediumTHEORETICAL5.4N5N6
QIF-T0129
Emotional flooding (affect overload)
Emotional processing therapy / exposure therapy (controlled activation)
mediumTHEORETICAL4.0N6
QIF-T0130
Empathy circuit disruption
TMS of temporoparietal junction for social cognition research
mediumTHEORETICAL5.4N6N7
QIF-T0131
Speech production hijacking
Speech neuroprosthesis / brain-to-speech BCI
mediumTHEORETICAL4.0N7
QIF-T0132
Comprehension interference
rTMS of Wernicke's area for tinnitus / auditory hallucinations
mediumTHEORETICAL4.0N7
QIF-T0133
Visual cortex overstimulation
Visual cortex prosthesis (Orion / Second Sight) / phosphene mapping
mediumTHEORETICAL5.4N7
QIF-T0134
Cochlear implant overstimulation
Cochlear implant therapy
mediumTHEORETICAL5.4I0N1
QIF-T0135
Neural pathway chaining (off-target propagation exploitation)
Connectome-informed DBS targeting / network-level stimulation
mediumTHEORETICAL5.4I0N1N2N3N4N5N6N7
QIF-T0136
Transcranial photobiomodulation (670/808nm)
Transcranial photobiomodulation for Parkinson's disease neuroprotection
lowCONFIRMED0.0I0N1
QIF-T0137
UCNP-mediated optogenetic dopamine release (980nm)
Deep brain optogenetic stimulation for Parkinson's disease
highDEMONSTRATED0.0I0N1N2N3
QIF-T0138
HUP photovoltaic nanoparticle dopamine stimulation (980nm)
Non-genetic deep brain photovoltaic stimulation
highEMERGING0.0I0N1N2N3
QIF-T0139
Photothermal gold nanoparticle TRPV1 dopamine activation
Wireless photothermal deep brain stimulation
mediumDEMONSTRATED0.0I0N1N2
QIF-T0140
Infrared neural stimulation (1875nm fiber contact)
Optical cochlear implant, infrared nerve stimulation
mediumCONFIRMED0.0I0N1
QIF-T0141
Magnetothermal nanoparticle TRPV1 stimulation (AMF)
Magnetothermal deep brain stimulation for Parkinson's
highDEMONSTRATED0.0I0N1N2N3
QIF-T0142
SICI-TMS GABA-A cortical inhibition (short-interval paired-pulse)
Diagnostic SICI for ALS, stroke biomarker
mediumCONFIRMED0.0I0N1
QIF-T0143
LICI-TMS GABA-B long-interval cortical inhibition (suprathreshold paired-pulse)
LICI biomarker for epilepsy, TBI
mediumCONFIRMED0.0I0N1
QIF-T0144
cTBS GABAergic LTD interneuron upregulation (theta-burst GABA increase)
cTBS for depression, chronic pain, post-stroke
highCONFIRMED0.0I0N1
QIF-T0145
Anodal tDCS polarity-specific GABA depletion (MRS-measured)
Anodal tDCS for stroke motor rehab, depression
mediumCONFIRMED0.0I0N1
QIF-T0146
Gamma-tACS PV-interneuron GABA-A modulation (40Hz contact entrainment)
Gamma-tACS for Parkinson's motor restoration
mediumDEMONSTRATED0.0I0N1
QIF-T0147
FUS thalamic GABAergic suppression (acoustic GABA reduction)
LIFU for essential tremor, disorders of consciousness
highDEMONSTRATED0.0I0N1N2
QIF-T0148
GENUS gamma-sensory entrainment of PV+ GABAergic interneurons (non-contact 40Hz)
GENUS for Alzheimer's (MIT/Cognito Therapeutics Phase 2/3)
mediumDEMONSTRATED0.0N1N2N3
QIF-T0149
Implanted VNS cholinergic cortical manipulation via nucleus basalis
VNS for epilepsy, depression, stroke rehab
highCONFIRMED0.0I0N1N2N3
QIF-T0150
Transcutaneous auricular VNS (tVNS) cholinergic modulation
tVNS for epilepsy, depression, Alzheimer's
mediumDEMONSTRATED0.0I0N1
QIF-T0151
TMS cholinergic cortical perturbation via mAChR (40-63ms TEP)
TMS-EEG biomarker for Alzheimer's cholinergic deficit
mediumEMERGING0.0I0N1
QIF-T0152
AChE inhibition BCI signal corruption (organophosphate exposure)
BCI-guided cholinergic crisis detection and countermeasure
criticalDEMONSTRATED0.0I0N1N2N3
QIF-T0153
Cholinergic medication status inference from BCI EEG spectral biomarkers
EEG pharmacodynamic biomarker monitoring
mediumTHEORETICAL0.0N1N2
QIF-T0154
VNS disynaptic serotonin upregulation (NTS->LC->DRN pathway)
VNS for treatment-resistant depression
mediumCONFIRMED0.0N1N2N3N4
QIF-T0155
Transcranial focused ultrasound DRN serotonin release (Piezo1/TRPA1 mechanotransduction)
tFUS for treatment-resistant depression via DRN
highEMERGING0.0I0N1N2N3
QIF-T0156
High-frequency electroacupuncture dorsal raphe serotonin drive (100Hz peripheral afferent)
Electroacupuncture for depression, chronic pain
mediumCONFIRMED0.0I0N1N2N3N4N5
QIF-T0157
Acute tryptophan depletion — serotonin precursor starvation via LAT1 competition
ATD challenge paradigm for depression vulnerability research
mediumCONFIRMED0.0N4N5N6N7
QIF-T0158
Silent excitatory/inhibitory ratio manipulation (sub-threshold seizure priming)
tDCS research (same parameters, different intent)
highTHEORETICAL0.0I0N1N2
QIF-T0159
LIFU astrocytic gliotransmission (acoustic TRPA1->extrasynaptic NMDA)
tFUS for depression, OCD, essential tremor
highEMERGING0.0I0N1N2
QIF-T0160
FUS-BBB breach as excitotoxic glutamate priming vector
FUS-BBB opening for Alzheimer's drug delivery, glioblastoma
criticalTHEORETICAL0.0I0N1N2N3
QIF-T0161
Cortical spreading depression initiation (autonomous glutamate wave)
CSD as migraine intervention target; ECT therapeutic mechanism
criticalEMERGING0.0I0N1N2N3