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QIF-T0153

medium

Cholinergic medication status inference from BCI EEG spectral biomarkers

Tier 5 — Theoretical (Modeled / Simulated)

Legacy status: THEORETICAL

Technique Details

Tactic
QIF-D.HV
Status
THEORETICAL
Bands
N1, N2

Therapeutic Application

EEG spectral signatures track cholinergic tone. 14-biomarker mAChR index achieves 88-92% accuracy detecting mAChR antagonist administration (Simpraga 2017). AChEI drugs produce drug-specific alpha/theta/beta patterns (Arjmandi-Rad 2024, 24-study review). Passive BCI data inference attack: infer medication status (donepezil = Alzheimer's diagnosis proxy), disease progression, acute cholinergic changes. No stimulation required.

Clinical Analog

EEG pharmacodynamic biomarker monitoring

Treats

  • Alzheimer's disease
  • cholinergic monitoring

Neural Impact

2 of 7 neural bands affected

N1 N2

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Scoring

NISS v1.1
0.0None

Validation Status

Theoretical / Not yet validated. This technique has not been independently tested. See the validation dashboard for what has been tested.

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